Designing Quality into Biopharmaceuticals

Onsite Training & Consulting
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Course Description

Companies that embrace Quality by Design (QbD) and a pharmaceutical quality systems approach are in a better position for successful biopharmaceutical operations, which translate into increased profits through reduced risks to customers and the business, as well as significantly reduced risks of costly deviation investigations or rejects and ensuing enforcement actions. It’s simple - designing quality into your product improves manufacturing outcomes.

As stated by FDA, “Quality cannot be tested into products; it should be built in or should be by design.” Learn how to establish the product and process design as part of a drug product life cycle to ensure that your organization’s medicinal products meet user needs, intended uses, and specified requirements. FDA, in the recent speeches by its leaders and in articles, has stressed its continually increasing focus on the QbD and Design Space approaches. This has been extended to include joint activities with the European Medicines Agency (EMA), as announced in March 2011. This approach is part of the ICH Q8, Q9, and Q10 guidelines.

For comprehensive training on the current regulatory expectations and an action plan for compliance and implementation, follow this course with Process Validation for Biopharmaceuticals (course code PVP).


CEUs:1.5
Number of days:2
Code:DQP
Cost:$1495.00

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Objectives
  • Understand FDA’s thinking on quality, safety, and efficacy being designed into the product.
  • Understand process design as a stage in the development and validation of a drug product to consistently meet quality requirements throughout its life cycle and for continuous improvement.
  • Review and compare aspects of design as stated in the ICH documents and FDA’s process validation guidance.
  • Describe activities connected with process design, development, and maintenance as they relate to the product life cycle.
  • Understand Design of Experiments (DOE) studies in the development of process knowledge and comprehension as the basis for process control.
  • Understand the role of testing and the establishment of acceptance criteria in drug and biological products design.
  • Define principles of modern FDA review processes: Quality by Design (QbD), Design Space, and Process Analytical Technology (PAT) as part of the pharmaceutical quality systems approach.
  • Recognize benefits of Design Space, PAT, and quality risk management principles in the drug development process.
  • Understand the use of the quality risk management process in the development of critical quality attributes of the drug product.
Topics
  • FDA, ICH, and process validation guidance
  • ICH guidance documents: Q6A and Q6B, Q8, Q9, and Q10
  • Assessment of product and process design
  • Design in the development of critical quality attributes
  • Elements of process design in the development, testing, and validation of a drug product
  • Risk management and CAPA
  • Quality systems approach to a drug product across its life cycle
Who Should Attend

This course is recommended for anyone managing, developing, or engaging in the design of pharmaceutical and biotechnology products, including direct engineering functions, QA/QC, production management, and regulatory, and any others who have a role in building a robust regulatory-compliant environment.

Upcoming dates and locations
Please contact us if you need additional information or if you don't see a date that works for you.
To register by phone, call 800.472.6477

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Course Name On-Site Public Dates
Location Start Date Days Cost Registration
Designing Quality into Biopharmaceuticals CONTACT US Chicago, IL 06/25/2012 2 $1495.00 Add to Cart
Designing Quality into Biopharmaceuticals CONTACT US San Francisco, CA 07/23/2012 2 $1495.00 Add to Cart
Designing Quality into Biopharmaceuticals CONTACT US Princeton, NJ 09/10/2012 2 $1495.00 Add to Cart
Designing Quality into Biopharmaceuticals CONTACT US Chicago, IL 09/24/2012 2 $1495.00 Add to Cart
 
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